PD-1/PD-L1 expression in anal squamous intraepithelial lesions
نویسندگان
چکیده
منابع مشابه
The Anal Pap Smear: Cytomorphology of squamous intraepithelial lesions
BACKGROUND: Anal smears are increasingly being used as a screening test for anal squamous intraepithelial lesions (ASILs). This study was undertaken to assess the usefulness and limitations of anal smears in screening for ASILs. METHODS: The cytomorphological features of 200 consecutive anal smears collected in liquid medium from 198 patients were studied and findings were correlated with resul...
متن کاملDNA methylation in anal intraepithelial lesions and anal squamous cell carcinoma.
PURPOSE Anal intraepithelial neoplasia is associated with human papillomavirus infection and may progress to invasive squamous cell carcinoma (SCC), which is increasing in immunocompromised patients. We hypothesize that anal intraepithelial neoplasia is associated with abnormal DNA methylation and that detection of these events may be used to improve screening programs. EXPERIMENTAL DESIGN Se...
متن کاملSquamous intraepithelial lesions
C ervical carcinoma is a significant contributor to cancer-related morbidity and mortality worldwide and the role of human papillomavirus (HPV) in the development of preinvasive and invasive cervical lesions is well established. 2 Although significant advances have been made in elucidating the potential mechanisms of cellular transformation by HPV and in the molecular detection of HPV in cytolo...
متن کاملHuman papillomavirus, anal squamous intraepithelial lesions, and human immunodeficiency virus in a cohort of gay men.
Cross-sectional associations between human papillomavirus (HPV), anal squamous intraepithelial lesions (SIL), and human immunodeficiency virus (HIV) were studied in a cohort of gay men. HPV DNA was detected by generic and type-specific polymerase chain reaction (PCR) probes and hybrid capture assay (HC). HPV virus load was estimated by HC relative light unit (RLU) ratio. HPV prevalence, number ...
متن کاملOral human papillomavirus infection in men who have sex with men with anal squamous intraepithelial lesions.
BACKGROUND Little is known about the association between oral and anogenital human papillomavirus (HPV) infections. METHODS Oral and anal samples from 66 men who have sex with men with a history of HPV-related anogenital squamous intraepithelial lesions were analyzed using polymerase chain reaction (PCR), and typed for 38 HPV types. RESULTS Prevalence of oral HPV infection was 30%, versus 8...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2020
ISSN: 1949-2553
DOI: 10.18632/oncotarget.27756